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Interrelation of Factors of Environmental and Biochemical Indexes of Blood

https://doi.org/10.25587/SVFU.2019.73.39421

Abstract

Studying of influence of factors of environmental pollution, including quality of the used water, on the state of health of the population is of interest. The purpose of the real work was assessment of degree of interrelation of biochemical parameters of blood with the index of tension of factors (ITF) (E.I. Burtsevа), reflecting complex assessment of state of environment taking into account influence of population, technogenic disturbances of the environment (the mountain weight taken from an earth subsoil, emissions of contaminants in the atmosphere, dumpings of the polluting sewage) and impurity of the used water. The research of the population of six Areas of Sakha (Yakutia) Republic (n=543) aged from from 18 to 50 years is conducted. The correlation analysis between values of the ITF index and chemicals of reservoirs and also their interrelation with biochemical parameters of blood is carried out. Direct correlation connection of ITF with content in water of sulfates (r=0.974), hardness of water (r=0.874), magnesium (r=0.864), nitrate ions (r=0.666) and the return correlation bonds with iron content (r = - 0.660), lead (r = - 0.562) and copper is established (r = - 0.553). Assessment of interrelation of biochemical parameters with INF revealed direct correlation bonds with the level of glucose (r=0.227), the general cholesterol (r=0.124), atherogenous lipoproteids of the low density lactate dehydrogenase (r=0.152), triglycerides (r=0.132). Significant direct correlation connection of content of copper in reservoirs is established with the level of an alkaline phosphatase (r=0.365), lactate dehydrogenase (r=0.148), ALT (r=0.182) and uric acid (r=0.162). At residents of those areas where high ITF of environmental pollution, substantial increase of level of glucose, general cholesterol, LDL and triglycerides is revealed, confirming failure of mechanisms of adaptation and high risk of cardiovascular diseases and endocrine disturbances.

About the Authors

A. S. Golderova
M.K. Ammosov North-Eastern Federal University
Russian Federation


S. D. Efremova
Yakut Scientific Center of Complex Medical Problems
Russian Federation


I. N. Nikolaev
M.K. Ammosov North-Eastern Federal University
Russian Federation


P. P. Hristoforov
M.K. Ammosov North-Eastern Federal University
Russian Federation


I. I. Mordosov
M.K. Ammosov North-Eastern Federal University
Russian Federation


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Review

For citations:


Golderova A.S., Efremova S.D., Nikolaev I.N., Hristoforov P.P., Mordosov I.I. Interrelation of Factors of Environmental and Biochemical Indexes of Blood. Vestnik of North-Eastern Federal University. 2019;(5):5-13. (In Russ.) https://doi.org/10.25587/SVFU.2019.73.39421

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ISSN 2222-5404 (Print)
ISSN 2587-5620 (Online)