Technologies of modern radiotherapy and development prospects. Quality assurance concept
https://doi.org/10.25587/2222-5404-2024-21-2-58-70
Abstract
At the clinic of the N.N. Blokhin National Medical Research Center of Oncology has been using the following conformal irradiation technologies for cancer patients that meet international standards for more than 13 years: 3D conformal radio therapy (3DCRT); intensity modulated radiotherapy (IMRT); volume modulated arc therapy (VMAT); stereotactic radiation technique (SRT); radiotherapy technique with breathing control, total therapeutic irradiation (TRT) technique followed by bone marrow transplantation. The technological complex with which these technologies are implemented has demonstrated an increase in the quality of radiation treatment for cancer patients. However, despite the “advancement” of technology, there are limitations in the ability to reduce dose loads on critical organs for a number of nosologies. Therefore, the prospects for the development of radiotherapy in Russia lie in the creation of several clinical centers for the use of heavy charged particles that have different physical and dosimetric characteristics and, from this point of view, carry other opportunities and prospects. There is great interest in flash therapy.
About the Author
I. M. Lebedenko
N.N. Blokhin National Medical Research Center of Oncology; National Research Nuclear University MEPHI
Russian Federation
Russian Federation
Irina M . Lebedenko – Dr. Sci. (Biol.), Assoc. Professor, Senior Researcher, Medical and Physical Support Service of the Radiotherapy Department; Professor, Department No. 35 of Medical Physics
Moscow
References
1. Ezzell GA, Galvin JM, Low D et al. Guidance document on delivery, treatment planning, and clinical implementation of IMRT: Report of the IMRT subcommittee of the AAPM Radiation Therapy Committee, Med. Phys., 2003;30:2090–2115.
2. Bedford JL. Treatment planning for volumetric modulated arc therapy, Med. Phys., 2009;36(11): 5128–5138.
3. Klein EE, Hanley J, Bayouth J et al. Task Group 142 report: Quality Assurance of Medical Accelerations, Med. Phys., 2009;36(9):4197–4212.
4. Islam M, Bernhard D, Smale J. et al. An integral quality monitoring system for real-time verification of intensity modulated radiation therapy, Med. Phys., 2009;36(12):4197–4212.
5. Alber M, Broggi S., Eichwurzel I. et al. Guidelines for the verification of IMRT // ESTRO booklet №9. – 2008.
6. Zhang X, Velasco C, Yany Y et al. SU-GG-T-294. Quality Assurance for Small SRS Photon Field Using Lucy Phantom of Brain Lab IPlan, Med. Phys., 2010;37.
7. Yarmonenko SP. Radiobiology of man and animals, Moscow: Higher School, 2004.
8. Podgorsak EB. Radiation oncology physics: a handbook for teachers and students, IAEA, 2005.
9. Melkova KN, Gorbunova NV, Chernyavskaya TZ et al. Total irradiation of the human body during bone marrow transplantation, Oncohematology, 2012;5(2):96–114.
10. Lebedenko IM, Ratner TG, Vodyanik VV et al. Technical and dosimetric support of total irradiation of patients before bone marrow transplantation, Med. Phys., 2012;3(55):11–19.
Review
For citations:
Lebedenko I.M. Technologies of modern radiotherapy and development prospects. Quality assurance concept. Vestnik of North-Eastern Federal University. 2024;21(2):58-70. (In Russ.) https://doi.org/10.25587/2222-5404-2024-21-2-58-70
Views:
156
Email this article 