Studying dynamics and function of ion channels is a field of interest of modern experimental molecular biology. At the same time, there are limited number of methods that allow studying the processes on molecular level with atomic precision. The most accurate methods that provide data on the atomic structure of molecules are the X-ray crystallography (XRC) and the nuclear magnetic resonance spectroscopy (NMR) methods. However, the XRC method provides data on the atomic structure of the crystallized molecule, while the crystallization conditions are usually far from physiological. Using structural data, obtained from the XRC/NMR methods, it is impossible to determine the state of the channel (open or closed) and analyze the dynamic of the processes under study. In this article, the molecular simulation methods are used to study the structure, dynamics and the diffusion processes on the water-membrane interface, as well as the process of ion transportation in 5-HT3 mouse serotonin 5HT-3 receptor, the spatial structure of which was determined in 2014. Based on the full-atom structure of the ion channel, we constructed the model, containing transmembrane domain of the 5-HT3 receptor with lipid bilayer and solvent. Molecular dynamics protocols for simulation of the transmebrane domain of the ion channel were developed. We used steered molecular dynamics for simulation of the transmembrane Na+ ion transport under external electric field. Using the umbrella sampling method, we estimated the free energy profile of Na+ ions transfer through the channel. Using the computer simulation methods (including molecular dynamics method) allowed us making reasonable assumptions about the conformation and conductive state of the ion channel under study.

The article presents data on the fauna of insects, birds, mammals in the the territory of Uyandinsky National Nasleg of Ust-Yansky District of Sakha Republic. On the basis of field studies and analysis of literature data, work has been done, which assesses the current state of the Nasleg fauna. The invertebrate fauna of the Yana river basin has not been studied enough and currently there are about 300 species in the lower reaches of the Yana River. To identify the species diversity of arthropods, basic entomological methods of harvesting were used: mowing by entomological net on grass and shrubs, Barber pitfall trap, individual collection by hands and exhauster entomological aspirator. It was found that in the area of studies inhabited by 36 species of 9 orders of insects. Currently, for the lower reaches of Yana, more than 130 species of birds are indicated. Ornithological observations were conducted on foot routes and on routes by vehicles and motor boats. In total, about 20 km of walking routes, more than 160 km of routes using water transport and 170 km using a vehicle have been covered. Widely used the method of interviewing local residents. The fauna of birds is presented by 119 species of 11 orders, of them, 17 species are registered in the Red Data book of Yakutia and 10 species are registered in the Red Data book of Russian Federation. The Teriofauna of the Ust-Yansky district includes 28 species of mammals. Most of these species are widespread throughout the taiga zone. To establish the species composition of small mammals standard methods were used: the animals were caught in grooves 20 m long, 20 cm wide, with 2 pitfall cones installed in them. In addition, trapping was used, installed in a line of 25 pieces every 5 m. Also used a method of interviewing local residents. Furthermore, stock materials and data on the accounting of hunting and commercial species in the Ust-Yansky district of the Republic Sakha (Yakutia) were used. Approximately 22-23 species of mammals is presented in area, further investigation is needed for full check-list of mammals.

Specially protected natural territories (PAs) have been created in the area: Resource Reserve (RR) "Suntar-Hayata" (66.6 thousand hectares), State Nature Reserve (GPP) "Tomporuk" (272.596 thousand hectares), GPP "Tukulan " (948,556 thousand ha), RR" Hotu " (3000 hectares). In Tomponsky region, the main forest-forming species is Cajander larch (Larix cajanderii Mayr.). Choseny and poplar forests, willow forests (Salix boganidensis Trautv., S. hastata L., S. alaxensis Coville.) Are located along the river valleys, and cedar elfin forests (Pinus pumila Regel.) On the tops of the ridge. There is a significant percentage of endemism among vascular plants (15 endemics and 6 subendemics). Often there are cryophilic steppes. The distribution of 98 taxa of moss from 63 genera and 25 families has been established on the territory of the “Suntar-Khayat” RR. The flora of the higher vascular plants of the Suntar-Hayat PP contains 231 species from 118 genera and 47 families. According to the preliminary list of vascular plant flora, 326 species, 177 genera, and 57 families were identified in the Tomporuk GPP. On the territory of the resource reserve “Hotu”, the growth of 226 taxa of vascular plants is possible, which are combined into 122 genera and 53 families. Of the vertebrate animals living in the Tomponsky region, 21 species of birds are listed in the Red Book of Yakutia, 2 species of mammals, 10 species of Insecta. The interaction of the Tompon Inspection of Nature Protection with scientific organizations, educational institutions, with the population includes participation, assistance in conducting expeditions, environmental studies, work with the district's authorities in the field of waste management, forest protection activities against fires, and environmental education work with the population. subsoil use enterprises, organization of summer environmental camps for schoolchildren with the involvement of scientific and pedagogical staff. At present, the Inspectorate, together with researchers from various RS (Y) institutions, prepared materials for the expansion of the territories of the GPP "Tomporuk", RR "Suntar-Hayat" and RR "Kuolum-Chappanda".

The article investigates coefficients of fractional parentage in j-representation, compulsory for the relativistic approach in the theory of multielectron atoms or multiply charged ions, in which the electrons are relativistic. The LS-coupling is broken in the relativistic approximation - the concepts of orbital and spin quantum numbers lose their meaning, that is, they become bad quantum numbers. The method of coefficients of fractional parentage is more convenient than the method of determinant functions, although it is more complex at first glance. The coefficients of fractional parentage in the j - representation allow us to obtain antisymmetric functions of the states of any N - electron j - subshell of equivalent electrons with any number of N-p and p electrons in these subshells. In principle, this makes it possible to study the matrix elements of an operator with any number of electrons (one-electron operator, two-electron operator, three-electron operator, etc.). The study of coefficients of fractional parentage is conducted in the formalism of the method of irreducible tensor operators using the method of secondary quantization. Simple relations have been received between coefficients of fractional parentage with p-number of split electrons and submatrix elements of p operators of the change in the number of electrons acting in double space - the space of angular momentum and quasispin. Working in double space allows obtaining analytical expressions for coefficients of fractional parentage in cases of subshells with two and three electrons. In cases of a larger number of electrons, simple recurrent relations between the coefficients of fractional parentage with any p-number of split electrons were obtained. The acquired recurrence relations allow us to find the values of the coefficients even in complex cases without resorting to the general procedure for finding them. Particularly, simple recurrence relations are obtained between the genealogical coefficients for partially and almost filled j-subshell. Simple recurrence relations are also gained in cases where the numbers of precedence are separately distinguished.

Almost immediately after the appearance of interest in carbon nanotubes (CNTs), research on inorganic nanotubes appeared. In 1992, the first results were obtained showing that nanotubular and fullerene-like structures are formed not only by carbon. In particular, the nanoparticles of the compound WS2, being unstable in a flat form, spontaneously form a closed structure related to fullerenes and CNTs. Later, such particles were synthesized from MoS2. Non-carbon nanotubes (NNT) are most often two-component compounds (BN, WS2, MoS2, SiC, etc.). Thus, a huge number of different compounds belong to the family of two-dimensional and one-dimensional materials, whose research is the actual task of modern science. In this paper, the synthesis of nanostructures is investigated by the method of gas-phase deposition (CVD-method), implemented using a Nabertherm tube furnace. The object of study is MoS2. The physicochemical parameters of the obtained nanostructures were studied using a JEOL JSM-7800F scanning electron microscope, a Nikon Eclipse LV 100 optical microscope and a SOLVER NEXT atomic force microscope. As shown by the results of the study, the obtained samples contained both particles of a molybdenum monolayer and tubular objects. The parameters affecting the growth of nanostructures were also established.

This paper reanalyzes the basic tonal patterns in French within the domain of Accentual Phrase (AP henceforth) and how the prosodic constraints for AP interact with those for the Intonational Phrase (IP). The level of Accentual Phrase (AP) and the higher level, the Intonational Phrase (IP) have been proposed in the earlier studies (Di Cristo & Hirst 1993, 1996, Delais-Roussarie 1996, Di Cristo 1999, Jun & Fougeron 2000, 2002, Post 2000, Rolland & Lœvenbruck 2002, Gussenhoven 2004, etc.). Employing the cyclic/stratal framework of Optimality Theory (Kiparsky 2000, Ahn 2008, etc.), we therefore suggest a path to overcome those shortcomings. In addition, we show that the possible indeterminacy problem occurring in the traditional autosegmental account can be easily solved by the interaction of constraints. Furthermore, by categorizing the phonetic factors as constraints, we can incorporate the phonetic details within our phonological categorization.

The focus of the paper is presented by the Yakut phraseological units with landscape components (subjects and concepts about the environment) - "earth, ground", "water", "tree", "forest", "mountain", "steppe", "fruit plant" in comparison with Turkic languages of South Siberia (Altaic, Tuvin, Khakass) and Kazakh language with the aim to determine lexical parallelisms of landscape component words, phraseosemantic types and phraseological parallels. In the phraseosemantic field "qualitative-evaluative characteristic of a person" the phraseosemantic types representing evaluative description of human ability: moral qualities, temperament, appearance, age, life experience, skills, social position, behavior etc., were found out. Using comparison and contrast methods we determined lexical parallels of landscape component words in Turkic languages, also in Mongolian and Tungus. Lexeme components denoting objects and concepts about the environment, as part of the Yakut phraseological units, which organize the phraseosemantic field “qualitative-evaluative characteristics of a person”, are 90% of the Turkic origin, words of Mongolian origin (mongolisms) are found in insignificant numbers. The lack of Manchurian-Tungus lexical parallels indicates a lack of interaction between the Yakut language and the Tungus-Manchurian languages in the formation of the fundamental concept of a MAN in the Yakut phraseological system. The presence of a certain number of similar semantically motivated phraseological units in the Yakut and Kazakh, Turkic languages of Southern Siberia indicates that the phraseological system of the Turkic languages has common ancient roots. At the same time, the similarity of associative images explains the same knowledge about world around and nature. The national specific phraseological units without parallels with related Turkic languages confirm the thesis about forming these units in noncontacting time. In prospect we see updating of the theoretical basis and methodology by Turkic phraseological comparativistics.

There are two reasons that predetermine the relevance of the topic: lack of psycholinguistic models of translation, more or less convexly focusing the mental stage of the source text message decoding and lack of domestic-coded translation meta-modelling as a type of mediation in intercultural communication. The latter, in particular, is caused by the traditional understanding of culture as a state belonging, not of the peoples living within the country. The research objective is to metamodel a domestic-coded translation grounded by a psycholinguistic approach to the study of mono- and intercultural communication. The goal is realized via the following steps: to give an overview of the existing models of translation due to the criterion “research paradigm”; to present initial methodological foundations of the algorithm, including a cognitive mechanism of natural semiosis; to present the author's psycholinguistic model focusing three mental operations to be realized at the preverbal stage of translation; to illustrate the model by examples and experimental data on Buryats’ communication strategies priorities. The main research method is modelling, the related methods are experiment, idealization, introspection, prediction, antithesis. Metamodelling testing is carried out by contradiction evidence, as well as Buryat-Russian translation examples and on the Yakut culture. The author comes to the conclusion that the psycholinguistic metamodel of domestic-coded translation provides an understanding what an atomic, microquantum approach to the study of semiosis is like; how equal is to translate cultures both at interstate and interdomestic levels. The model might work in interpretation and translation, when the intermediary between cultures suppresses their self-interpretation and subsequently perceives the sender’s and recipient’s internal worldviews in the source text back topic. The research prospects might develop as the metamodel testing via observations the way other languages of Russia are translated into Russian.

The article deals with the history of the formation of a special translation related to the translation of scientific and technical texts. The special translation has gone a long way of historical development, which is closely connected with the development of language, culture, philosophy and science in general. In modern science, an important integrative approach has emerged to the study and modeling of the translator's activity, in which researchers take into account the achievements of the neighboring disciplines related to translation. The use of a special translation of the traditional methods of historiography made it possible to interpret this type of translation from the standpoint of the experience of knowledge of history, the formation of ideas about translation in the space of culture, scientific and philosophical thought, and to supplement the traditional linguistic analysis of the translator’s activities with historical and cultural approaches. The analysis made it possible to determine the stages of the formation of a special translation in the ancient world and the Middle Ages before the spread of the translation into European languages. The translations in the field of science and philosophy in ancient Greece and the Roman Empire were considered, then the features of the activities of translators in the Arab School of wisdom were analyzed. The features of a special translation at each of the considered stages, translated materials, methods and methods of translation and requirements for translators are disclosed. The last stage considered in the article (Toledo Translation School) united the culture of two different communities (Christian and Muslim worlds). Translations of scientific texts from the Greek and Arabic languages allowed to overcome the lag in the field of culture and science of Western Europe from the Arab world and served as a guarantor of the transfer of knowledge of the ancient world. This knowledge came to Russia from Byzantium after the adoption of Christianity in Russia. The ancient heritage was assimilated in the Byzantine version, which cut off Ancient Russia (and then Russia) from the ancient heritage in its original form. And only later after the fall of the Tatar-Mongol and the unification of the Russian lands in Moscow State were the prerequisites for the development of national culture, and thus for the development of science and technology. Translations of philosophical and scientific works of ancient authors began to appear in Russia, but through translations of European states.

The relevance of the study is due to the importance of “Blizzard” dreams and dreamy insights suggested by the snowstorm in the artistic system of L. Tolstoy and Russian literature of the XIX century as a whole. On the material of the story “Master and Man” were considered the main strategy of existential behavior of the characters. The truth of the chosen path is verified by the test of the winter element and the collision with death, and the ability to spiritual transformation is directly related to the ability to interpret the signs of fate that are in dreams. In the course of the study it was found that the epistemological concept of L. Tolstoy is reflected in the dreams of the characters. The subject of the study in the article are the dreams of the characters of the story of Leo Tolstoy, which illustrate the process of finding the truth. Genesis Epiphany occurs in a dream and is the result of a unique process of knowledge presented in the works of Leo Tolstoy - identification with others. Through the identification of the owner with the employee, it becomes possible to move from a false life “for oneself” to a life “for others” and approach the true Master of being. The necessary context is represented by the dreams of the characters of the works of L. Tolstoy and other writers that make up the «Blizzard» text of Russian literature. In the course of the study, structural-semiotic, mythopoetic, comparative-historical methods were applied, as well as methods of motivational analysis were used. It seems promising to further study the connection of dreams with a Blizzard in the space of Russian literature, allowing to penetrate into the artistic anthropology of writers.